九色堂

I am a mammalian reproductive biologist with a fundamental interest in ovarian function. This includes: the mechanisms underlying folliculogenesis focusing on the role of somatic cells in regulating this process; factors governing early embryo development; clinical infertility; and ovarian cancer. I am part of a NIH-funded Program Project investigating the differential activity and function of human FSH glycoforms upon reproductive function and how these glycoforms change as a function of age. Numerous techniques are utilized to address the above research areas including primary cell culture, molecular biology, biochemistry, and morphological analysis.

Courses Taught Previously

BIOL 210	General Biology I
BIOL 420	Molecular Cell Biology
BIOL 526	Endocrinology
BIOL 540	Developmental Biology
BIOL 590	Immunobiology
BIOL 626/640	Reproductive Biology

 

1. Bousfield, G. R., May, J. V., Davis, J. S., Dias, J. A., & Kumar, T. R. 2018. In vivo and in vitro impact of carbohydrate variation on follicle-stimulating hormone function. Front. Endocrinol., 9, 216.
2. Wang, H., May, J., Shuai, B., May, J. V., Bousfield, G. R., & Kumar, T. R. 2016. Evaluation of in vivo bioactivities of recombiant hypo-(FSH21/18) and fully- (FSH24) glycosylated human FSH glycoforms in Fshb null mice. Mol. Cell. Endocrinol., 437, 224-236.
3. Jiang, C., Hou, X., Wang, C., May, J. V., Butnev, V. Y., Bousfield, G. R., & Davis, J. S. 2015. Hypo-glycosylated hFSH has greater bioactivity than fully-glycosylated recombinant hFSH in human granulosa cells. J. Clin. Endocrinol. Metab., 100(6), e852-E860.
4. Butnev, V. Y., Butnev, V. Y., May, J. V., Shuai, B., Tran, P., White, W. K., & Bousfield, G. R. Production, purification, and characterization of recombinant hFSH glycoforms for functional studies. Mol. Cell. Endocrinol., 405, 41-52.
5. Davis, J. S., Kumar, T. R., May, J. V., & Bousfield, G. R. 2014. Naturally occurring follicle-stimulating hormone glycosylation variants. J. Glycomics Lipidomics, 4, e117.
6. Bousfield, G.R., Butnev, V.Y., Butnev, V.Y., Hiromasa, Y., Harvey, D.J., & May, J.V. 2014. Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24). Mol. Cell. Endocrinol., 382, 989-997.
7. Alwis, I.D., Maroni, D.M., Hendry, I.R., Roy, S.K., May, J.V., Leavitt, W.W., & Hendry, W.J., 2011. Neonatal Diethylstilbestrol Exposure Disrupts Female Reproductive Tract Structure/Function Via Both Direct And Indirect Mechanisms In The Hamster.  Reprod. Toxicol., 32(4), 472-483.

 

Year(s)	Position Held
2002 - 2009	Associate Professor, Dept. of Biological Sciences, 九色堂, Wichita, KS
2002 - 2004	Executive Director, H.L. Snyder Medical Research Institute, Winfield, KS
1993 - 2002	Scientific Director, The Women's Research Institute, Wichita, KS
1987 - 2002	Senior Scientist, The Women's Research Institute, Wichita, KS
1991 - 2002	Associate Professor, Dept. of Ob/Gyn, Un. of KS School of Medicine-Wichita, Wichita, KS
1995 - 2002	Adjunct Professor, Dept. of Biological Sciences, 九色堂, Wichita, KS
1988 - 1997	Director, Assisted Reproductive Technology Lab, The Center for Reproductive Medicine, Univ. of KS School of Medicine-Wichita, Wichita, KS
1987 - 1991	Assistant Professor, Dept. of Ob/Gyn, Univ. of KS School of Medicine-Wichita, Wichita, KS
1982 - 1987	Assistant Professor of Ob/Gyn (non-tenure track) and Assistant Professor of Physiology, Duke University Medical Center, Durham, NC

 

Honors and Other Activities

Kansas-IDEA Network of Biomedical Research Excellence (K-INBRE): Faculty Scholar Award, 3/1/2007
NIH Study Section- Regular, 4-year Membership:
Previous - RAG, 10/15/2008 鈥� 6/30/2012, extended through 2013
Previous - REB , 09/12/1994-06/30/1998

NIH Ad Hoc Member: RAG, 6/25-26/2007; ICER, 10/5-6/2006; CMIR, 6/21-22/2004; REB, 06/02-04/2003, 10/04-06/1993; 6/23-23/1993; BCE, 05/10-12/1992

NIH Special Study Sections: Cooperative Specialized Infertility Research Center Program (U-54), NICHD, 4/8-11/1996; P-50 Site Visit Team DRG, NIH 9/28-30/1995; Special Emphasis Panel, NICHD, NIH, 4/24/1998; Special Emphasis Panel, CSR, NIH, SBIR/STTR Grant Review, 3/29-30/1999 and 11/15-16/1999, Special Emphasis Review Panel, K08 grant review, 7/31/2002.

NIH Ad Hoc Grant Reviewer: MABS, 3/2005, 10/2005, 10/2006; EMNR-A02M, 10/2005; BCE, 12/1989, 5/1991.

Grant Reviewer: USDA 04/1990, 05/1991; and NSF 09/19/90.

Editorial Board: Endocrinology 1993-1996; American Journal of Physiology (Endocrinology/Metabolism) 1995-1997, 1998-2002

Consultant: Food and Drug Administration, DHHS, Ob/Gyn Devices Panel, 1996-2004

High Complexity Clinical Lab Director (HCLD) The American Board of Bioanalysis, 1994-2000

Laboratory Inspector, Reproductive Accreditation Program, College of American Pathologists, 1993-1996

 

Grant #: 5P01-AG029531-07 [NIH, NIA] (Bousfield, PI)	09/01/17 - 05/31/22	Title: The Aging Pituitary/Gonadal Axis	$1,709,158 /5 yr	Roles: Co-Leader, Core A-Administrative Core Leader, Core B - FSH Preparation, Purification and Analysis Laboratory
K-INBRE Core Facility Award	05/10/19 - 04/30/20	Title: 九色堂 P01 Core Lab Cell Counter	$8,018	Role: Principal Investigator
K-INBRE Core Facility Award	05/01/17 - 04/30/18	Title: 九色堂 P01 Core Lab Ultralow -80C Freezer	$10,081	Role: Principal Investigator
Grant #: 5P01-AG029531-02 [NIH, NIA] (Bousfield, PI)	03/01/09 - 02/28/14	Title: The Aging Pituitary/Gonadal Axis	$6,622,855 /5 yr	Roles: Co-Leader, Core A-Administrative Core Leader, Core B - FSH Preparation, Purification and Analysis Laboratory
K-INBRE  Translational Parnershp Pair Grant	04/01/12 - 03/31/13	Diagnostic Relevance of Human Urinary FSH Glycoform Assessment to Ovarian Aging	$37,500	Role: Principal Investigator
K-INBRE Core Facility Grant	05/01/11 - 04/30/12	Title: 九色堂 P01 Core Lab Roller Bottle Incubator	$18,557	Role: Principal Investigator
Grant #: 1G20RR031092-01 [NCRR] (Hendry, PI)	07/01/10 - 06/30/11	Title: 九色堂 Combined Core Facility Renovation Project	$2,109,094 /2 yr.	Role: Grant Proposal Author & Project Manager. The application was organizae and written entirely by Dr. May who is responsible for progress and completion of the project.

 

• Adjunct Associate Professor, Dept. of Medical Sciences, School of Medicine-Wichita, University of Kansas Medical Center, Wichita, Kansas